Separation and purification in organic solvents are indispensable procedures in pharmaceutical manufacturing. Organic solvent nanofiltration (OSN) offers a low energy, low waste generating, and easily scalable alternative to the conventional method sof distillation or chromatography. A newly open-access published review from ETERNAL partners AstraZeneca comprehensively summarizes the recent progress of organic solvent nanofiltration and its applications in the pharmaceutical industry.

As part of the comprehensive industrial cocreation process through which ETERNAL’s case studies are being steered, Britest is developing a methodology which variously helps innovators to find the most sustainable process route when faced with multiple possibilities, to identify and challenge environmental impacts, and to develop cost effective carbon footprint reduction plans across their products’ value chain.