Angelini Pharma has used Twin Screw Granulation successfully used to produce granules for immediate-release tablets with fewer steps and less materials, avoiding water addition and energy-intensive phases, as a potential alternative to the current batch manufacturing process.

AstraZeneca has developed a process using organic solvent nanofiltration (OSN) membrane technology to efficiently recover and reuse palladium catalysts during the synthesis of an important oncology drug. This minimizes energy consumption and waste production, promoting a more sustainable approach to catalyst management in pharmaceutical manufacturing.

Organic solvent nanofiltration (OSN) offers an energy-efficient alternative to distillation, using membrane technology to achieve low temperature, low energy solvent exchange. Coupled with inline Fourier Transform infrared spectroscopy (FTIR), solvent composition can be monitored dynamically, enhancing the overall process efficiency.

This video describes how concerted efforts in ETERNAL's case studies distributed across a range of industrial use cases and the extended value chain for pharmaceuticals are making a real and positive impact upon the future sustainability and competitiveness of the sector.

The latest scientific paper produced by researchers in the ETERNAL project emphasises the potential role of enzymes in supporting the transition towards a more sustainable future pharmaceutical industry.